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DSIP Compound

A dark, instrument-panel reading of the delta sleep-inducing peptide literature — every EEG, HPA-axis, and insomnia study, logged and counted.

DSIP SOURCES / PAGE 08

DSIP references you can check yourself

You’ll find the full study details and a link for every numbered source.

Return to the studiesSee how we read them

What these sources let you check

Every number and study claim points to a source below. You can check the dose, length, group, and result.

The list starts with the 1977 rabbit study. It also covers human work from the 1980s and 1990s.

You’ll find hormone, mouse life-span, and 2024 mouse studies too. Each item names its authors, journal, year, and pages.

The PMID or DOI helps you find the original paper. Those letter and number tags are kept in the source list.

You don’t need to know those tags to read a paper. They simply help you reach the exact source we used.

  1. Schoenenberger GA, Monnier M. Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. Proc Natl Acad Sci U S A. 1977;74(3):1282-1286. ↗
  2. Schneider-Helmert D, et al. The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep. Experientia. 1981;37(8):913-914. ↗
  3. Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. 2006;97(2):303-309. ↗
  4. Bjartell A, Ekman R, Bergquist S, Widerlov E. Reduction of immunoreactive ACTH in plasma following intravenous injection of delta sleep-inducing peptide in man. Psychoneuroendocrinology. 1989;14(5):347-355. ↗
  5. Popovich IG, Voitenkov BO, Anisimov VN, et al. Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice. Mech Ageing Dev. 2003;124(6):721-731. ↗
  6. Mu X, Qu L, Yin L, Wang L, Liu X, Liu D. Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models. Front Pharmacol. 2024;15:1439536. ↗
  7. Schneider-Helmert D. Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study. Neuropsychobiology. 1992;26(4):230-233. ↗
  8. Schneider-Helmert D. Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia. Eur Neurol. 1987;27(2):120-129. ↗
  9. Schneider-Helmert D. A clinical trial with DSIP. Eur Neurol. 1984;23(5):358-363. ↗
  10. Schneider-Helmert D. Efficacy of DSIP to normalize sleep in middle-aged and elderly chronic insomniacs. Eur Neurol. 1986;25(2):154-157. ↗
  11. Schneider-Helmert D. The use of DSIP (delta sleep-inducing peptide) in the correction of phase-shifted insomnia. Dtsch Med Wochenschr. 1987;112(20):779-783. ↗
  12. Vorob'ev VV, Shibaev NV, Prudchenko IA, Mikhaleva II. [The frequency composition of the brain electrical activity in rats after the use of the delta-sleep peptide and its analogs]. Zh Vyssh Nerv Deiat Im I P Pavlova. 1992;42:977-985. ↗
  13. Gupta BB, Seidel A, Spessert R, et al. In vitro effects of putative neurotransmitters on synaptic ribbon numbers and N-acetyltransferase activity in the rat pineal gland. J Neural Transm Gen Sect. 1992;89:167-178. ↗
  14. Sudakov KV. [The antistress effects of the delta sleep-inducing peptide]. Fiziol Zh SSSR Im I M Sechenova. 1991;77:1-13. ↗
  15. Bjartell A, Sundler F, Ekman R. Immunoreactive delta sleep-inducing peptide in the rat hypothalamus, pituitary and adrenal gland: effects of adrenalectomy. Horm Res. 1991;36:52-62. ↗